Gluten and Schizophrenia

The idea that gluten consumption may influence the development of schizophrenia has been the subject of a bit of discussion lately (1). Much of the speculation comes from the increased rates of gluten intolerance and celiac disease like symptoms found in schizophrenics (2,3). One major hypothesis postulates that when gluten derived peptides known as exorphins enter the blood they disturb brain function and cause schizophrenia (4,5). And while there is a correlation between gluten intolerance and schizophrenia, it’s merely that; a correlation. Not much evidence exists proving causality. It is possible that gluten is responsible, but it could be that both are symptoms of the same underlying cause. Let me explain. Continue reading